AirPods Pro 3

Xiaokang Chen, Zhiyu Wu, Xingchao Liu, Zizheng Pan, Wen Liu, Zhenda Xie, Xingkai Yu, C. Ruan

In this work, we introduce Janus-Pro, an advanced version of the previous work Janus. Specifically, Janus-Pro incorporates (1) an optimized training strategy, (2) expanded training data, and (3) scaling to larger model size. With these improvements, Janus-Pro achieves significant advancements in both multimodal understanding and text-to-image instruction-following capabilities, while also enhancing the stability of text-to-image generation. We hope this work will inspire further exploration in the field. Code and models are publicly available.

Rob L Shaver, M. Buonomo, Joseph A. Scherman, A. Neeley

Contact allergy to acrylates in Apple AirPods Pro headphones: A case series Dear Editor, Apple AirPods are the best-selling wireless headphones on the market. A recent case report described one case of allergic contact dermatitis (ACD) associated with the original (1st/2nd generation) AirPods . Patch testing implicated acrylates as the primary allergen. We present four additional cases of ACD to Apple AirPods devices. Each patient below was patch tested according to the North American Contact Dermatitis Group (NACDG) protocol. A 35-year-old male presented with a 7-month history of rash on the ears which he attributed to his Apple AirPods Pro

L. Lee, W. Koh, S. Lim

Amandine Baudy: Conceptualization (lead); data curation (equal); formal analysis (equal); resources (lead); writing – original draft (lead); writing – review and editing (lead). Olivier Dereure: Methodology (equal); supervision (equal); validation (equal); writing – review and editing (equal). Aurelie Du-Thanh: Conceptualization (lead); data curation (equal); methodology (equal); resources (lead); supervision (lead); validation (lead); writing – review and editing (lead). Nadia Raison-Peyron: Conceptualization (lead); data curation (equal); methodology (equal); resources (lead); supervision (lead); validation (lead); writing – review and editing (lead).

Joaquin T. Valderrama, Jorge Mejia, Angela Wong, N. Chong-White, B. Edwards

Abstract Objective To investigate the extent to which Headphone Accommodations in Apple AirPods Pro attend to the hearing needs of individuals with normal audiograms who experience hearing difficulties in noisy environments. Design Single-arm interventional study using acoustic measures, speech-in-noise laboratory testing, and real-world measures via questionnaires and ecological momentary assessment. Study sample Seventeen normal-hearing individuals (9 female, 21–59 years) with self-reported hearing-in-noise difficulties. Results Acoustic measures showed that, relative to unaided, AirPods Pro provided a SNR advantage of +5.4 dB. Speech intelligibility performance in laboratory testing increased 11.8% with AirPods Pro, relative to unaided. On average, participants trialling AirPods Pro in real-world noisy venues reported that their overall hearing experience was a bit better than without them. Five participants (29%) reported that they would continue using AirPods Pro in the future. The most relevant barriers that would discourage their future use were limited hearing benefit, discomfort, and stigma. Conclusions Occasional use of AirPods Pro may help some individuals with normal audiograms ameliorate their speech-in-noise hearing difficulties. The identified barriers may inspire the development of new technological solutions aimed at providing an optimal management strategy for the hearing difficulties of this segment of the population.

Yusuke Sato, Yuri Aiba, Sayaka Yajima, Takaaki Tanabe, K. Higuchi, S. Nishizawa

The RNA promoter region of the influenza A virus has recently attracted much attention as an RNA target for the development of anti‐influenza drugs. However, there are very few reports on small RNA‐binding ligands targeting this region. In this work, it is reported that TO‐PRO‐3, a thiazole orange analogue with a trimethine bridge, exhibits strong and selective binding to the internal loop structure of the influenza A virus RNA promoter. This binding accompanies the remarkable light‐up response of TO‐PRO‐3 in the deep‐red spectral region. By virtue of these binding and fluorescence signaling functions, TO‐PRO‐3 can act as a useful indicator for the assessment of the binding capabilities of various test compounds for this RNA region, with a view toward the development of anti‐influenza drug candidates.