行谷時男

Shinichi 進一 Kuriyama 栗山, Nobuo 伸生 Yaegashi 八重樫, Fuji 風二 Nagami 長神, Tomohiko 知彦 Arai 新井, Yoshio 悦生 Kawaguchi 川口, Noriko 典子 Osumi 大隅, Masaki 正樹 Sakaida 境田, Yoichi 洋一 Suzuki 鈴木, Keiko 啓子 Nakayama 中山, Hiroaki 拓明 Hashizume 橋詰, Gen 元 Tamiya 田宮, Hiroshi 裕 Kawame 川目, Kichiya 吉也 Suzuki 鈴木, Atsushi 篤 Hozawa 寳澤, Naoki 直樹 Nakaya 中谷, Masahiro 昌浩 Kikuya 菊谷, Hirohito 弘仁 Metoki 目時, Ichiro 一郎 Tsuji 辻, Nobuo 昇男 Fuse 布施, Hideyasu 秀泰 Kiyomoto 清元, Junichi 準一 Sugawara 菅原, Akito 明人 Tsuboi 坪井, Shinichi 新一 Egawa 江川, Kiyoshi 潔 Ito 伊藤, Koichi 浩一 Chida 千田, Tadashi 正 Ishii 石井, Hiroaki 博秋 Tomita 富田, Yasuyuki 靖之 Taki 瀧, Naoko 直子 Minegishi 峯岸, Naoto 直人 Ishii 石井, Jun 純 Yasuda 安田, Kazuhiko 和彦 Igarashi 五十嵐, Ritsuko 律子 Shimizu 清水, Masao 正朗 Nagasaki 長﨑, Seizo 生造 Koshiba 小柴, Kengo 賢吾 Kinoshita 木下, Soichi 創一 Ogishima 荻島, Takako 貴子 Takai-Igarashi 高井, Teiji 悌二 Tominaga 冨永, Osamu 修 Tanabe 田邉, Noriaki 憲明 Ohuchi 大内, Toru 徹 Shimosegawa 下瀬川, Shigeo 繁夫 Kure 呉, Hiroshi 博 Tanaka 田中, Sadayoshi 貞嘉 Ito 伊藤, Jiro 次郎 Hitomi 人見, Kozo 高三 Tanno 丹野, Motoyuki 元行 Nakamura 中村, Kuniaki 邦昭 Ogasawara 小笠原, Seiichiro 誠一郎 Kobayashi 小林, Kiyomi 清美 Sakata 坂田, Mamoru 衛 Satoh 佐藤, Atsushi 厚 Shimizu 清水, Makoto 真理 Sasaki 佐々木, Ryujin 龍人 Endo 遠藤, Kenji 憲治 Sobue 祖父江, Masayuki 雅之 Yamamoto 山本

The Great East Japan Earthquake (GEJE) and resulting tsunami of March 11, 2011 gave rise to devastating damage on the Pacific coast of the Tohoku region. The Tohoku Medical Megabank Project (TMM), which is being conducted by Tohoku University Tohoku Medical Megabank Organization (ToMMo) and Iwate Medical University Iwate Tohoku Medical Megabank Organization (IMM), has been launched to realize creative reconstruction and to solve medical problems in the aftermath of this disaster. We started two prospective cohort studies in Miyagi and Iwate Prefectures: a population-based adult cohort study, the TMM Community-Based Cohort Study (TMM CommCohort Study), which will recruit 80 000 participants, and a birth and three-generation cohort study, the TMM Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study), which will recruit 70 000 participants, including fetuses and their parents, siblings, grandparents, and extended family members. The TMM CommCohort Study will recruit participants from 2013 to 2016 and follow them for at least 5 years. The TMM BirThree Cohort Study will recruit participants from 2013 to 2017 and follow them for at least 4 years. For children, the ToMMo Child Health Study, which adopted a cross-sectional design, was also started in November 2012 in Miyagi Prefecture. An integrated biobank will be constructed based on the two prospective cohort studies, and ToMMo and IMM will investigate the chronic medical impacts of the GEJE. The integrated biobank of TMM consists of health and clinical information, biospecimens, and genome and omics data. The biobank aims to establish a firm basis for personalized healthcare and medicine, mainly for diseases aggravated by the GEJE in the two prefectures. Biospecimens and related information in the biobank will be distributed to the research community. TMM itself will also undertake genomic and omics research. The aims of the genomic studies are: 1) to construct an integrated biobank; 2) to return genomic research results to the participants of the cohort studies, which will lead to the implementation of personalized healthcare and medicine in the affected areas in the near future; and 3) to contribute the development of personalized healthcare and medicine worldwide. Through the activities of TMM, we will clarify how to approach prolonged healthcare problems in areas damaged by large-scale disasters and how useful genomic information is for disease prevention.

芝燕 李

東園 雄太, 坂本 瑞樹, 小川 和真, 尾崎 和基, 大山 亮平, 郷田 到, 鶴沼 太朗, 庄司 多津男, 芦川 直子, 時谷 政行, 徳永 和俊, 増崎 貴, 大宅 薫, 相良 明男

坂本 瑞樹, 宮崎 俊昌, 東園 雄太, 小川 和真, 尾崎 和基, 庄司 多津男, 芦川 直子, 時谷 政行, 増崎 貴, 徳永 和俊, 大宅 薫, 相良 明男, 佐藤 浩之助

蔡伶甄